Dean Sheppard

Dean Sheppard

Company: University of California, San Francisco

Job title: Chief of Pulmonary, Critical Care, Allergy & Sleep & Director of Lung Biology Center


Keynote: Targeting Integrin Tethering of Airway Smooth Muscle to Treat Exaggerated Airway Narrowing 9:15 am

Current and emerging treatments for asthma target actin-myosin contraction or upstream inflammatory mediators To narrow the conducting airways, contracting airway smooth muscle must be tightly tethered to the underlying ECM Inhibition of integrins on airway smooth muscle cells can dramatically reduce airway narrowing and enhance the effects of existing brochodilatorsRead more

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